Quality of life and breast reconstruction study (QoLID)
To investigate the quality of life of women who have chosen to have immediate or delayed breast reconstruction, or no breast reconstruction, after mastectomy and before having radiotherapy, for breast cancer.
The objectives of this study have been to investigate:
(a) Whether there is a difference in quality of life between patients who have chosen different reconstruction options (immediate or delayed);
(b) Whether there is a difference in quality of life between patients who have chosen either reconstruction option (immediate or delayed) compared with no reconstruction; and
(c) How patients’ quality of life has been affected by their reconstruction choices and any surgical complications.
A prospective Quality of Life study of Immediate & Delayed breast reconstruction in women undergoing mastectomy and adjuvant radiotherapy for breast cancer (QoLID study).
Radiotherapy has a detrimental effect on outcomes from breast reconstruction for some women, especially for women undergoing implant based reconstruction. For this reason, some surgeons recommend delaying radiotherapy until after other (adjuvant) breast cancer therapy is complete. This is a controversial issue with little good evidence to support the best approach.
Women’s perceptions of the impact of breast reconstruction outcomes and impact on their quality of life are particularly relevant. This study aimed to provide a direct comparison to assess the quality of life impact of immediate reconstruction, delayed reconstruction and no reconstruction in women undergoing mastectomy and post mastectomy radiotherapy for breast cancer by using a comprehensive set of patient reported outcome measures.